After a hair-raising journey, Dr. Mary Davis arrives in a remote Himalayan village with just a backpack and a box of medicines. Expecting to work with a talented Indian surgeon, she finds instead that he is missing and she is now the only doctor for a hundred miles. When an injured tourist stumbles in her overcrowded clinic, he triggers a series of events that connects an unusual mix of characters: Phillip, the spoiled son of a British diplomat; Antone, an aging addict who attempts to kidnap him; Meena, a local village girl who embarks on an improbable rescue; and Amod, the lonely waiter in the local dhaba, who secretly looks after Mary.